Multi-omics technology for demystifying herbal medicine

Herbal medicine (HM) is a fruitful source of chemical substances that has contributed greatly to the pharmaceutical industry and novel therapeutics. Natural products derived from HM continue be rich lead compounds because their high structural diversity potent bioactivities. However, despite success active ingredients in drug discovery, compatibility issues make huge challenging for extended timelines effective evaluation, composition identification, ingredient screening target confirmation. some approaches solely cannot effectively elucidate overall effect action mechanism due complexity muti-components HM. Thus, integration strategies combining modern analytical techniques with are increasingly being developed era big data omics. The updated mass spectrometry been used identify natural product structure mode on biological processes. Their molecular properties validated through use recent high-throughput multi-omics including transcriptomic, proteomic metabolomic tools bio-informatics, docking, network pharmacology enable accelerate discovery. We summarized several important omics technical platforms multi-omics-based approach as powerful demystify discover new bioactive molecules.